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2025-26 Men’s Second Rounds Odds: Spreads, L...

We’re diving into the second round of basketball’s greatest Tournament. 

Let’s check out the odds for the men’s NCAA Tournament Round of 32 at DraftKings Sportsbook as of March 22.

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

SATURDAY, MARCH 21

No. 9 Saint Louis 72, No. 1 Michigan 95

Spread: Michigan -12.5 (Michigan covers)
O/U: 161.5 (Over hits)

No. 9 TCU 58, No. 1 Duke 81

Spread: Duke -12.5 (Duke covers)
O/U: 140.5 (Under hits)

No. 10 Texas A&M 57, No. 2 Houston 88

Spread: Houston -11.5 (Houston covers)
O/U: 143.5 (Over hits)

No. 11 Texas 74, No. 3 Gonzaga 68

Spread: Gonzaga -6.5 (Texas covers)
O/U: 147.5 (Under hits)

No. 11 VCU 55, No. 3 Illinois 76

Spread: Illinois -10.5 (Illinois covers)
O/U: 151.5 (Under hits)

No. 6 Louisville 69, No. 3 Michigan State 77

Spread: MSU -5.5 (MSU covers)
O/U: 150.5 (Under hits)

No. 12 High Point 88, No. 4 Arkansas 94

Spread: Arkansas -11.5 (HPU covers)
O/U: 169.5 (Over hits)

No. 5 Vanderbilt 72, No. 4 Nebraska 74

Spread: Vandy -1.5 (Nebraska covers)
O/U: 146.5 (Under hits)

SUNDAY, MARCH 22

No. 9 Utah State vs. No. 1 Arizona

Spread: Arizona -11.5
Moneyline: Arizona -800, Utah State +550
O/U: 154.5

No. 9 Iowa vs. No. 1 Florida

Spread: Florida -10.5
Moneyline: Florida -625, Iowa +455
O/U: 145.5

No. 7 Kentucky vs. No. 2 Iowa State

Spread: Iowa State -5.5
Moneyline: Iowa State -238, Kentucky +195
O/U: 146.5

No. 7 UCLA vs. No. 2 UConn

Spread: UConn -4.5
Moneyline: UConn -198, UCLA +164
O/U: 136.5

No. 7 Miami FL vs. No. 2 Purdue

Spread: Purdue -7.5
Moneyline: Purdue -375, Miami +295
O/U: 146.5

No. 6 Tennessee vs. No. 3 Virginia

Spread: Tennessee -1.5
Moneyline: Tennessee -115, Virginia -105
O/U: 137.5

No. 5 St. John’s vs. No. 4 Kansas

Spread: St. John’s -3.5
Moneyline: St. John’s -175, Kansas +145
O/U: 144.5

No. 5 Texas Tech vs. No. 4 Alabama

Spread: Texas Tech -1.5
Moneyline: TTU -112, Alabama -108
O/U: 164.5

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